Equine hyperlipidemia

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Equine Hyperlipidemia

Equine hyperlipidemia is a severe, life-threatening medical condition that is seen predominately in miniature horses, donkeys and ponies. It occurs as a result of a sudden and significant breakdown of body fat stores. Adult female animals with insulin resistance (IR), pregnant, or increased nutrient demands have a predisposition to Hyperlipidemia. Trigger factors for predisposed individuals include stress, pain, disease, inadequate feed intake, feed changes, and transportation. Secondary hyperlipemia can occur with enterocolitis, dental disease, bacterial infections, colic impactions, and parasitism. Secondary complications of hyperlipemia include hypovolemia, electrolyte imbalances and hepatorenal insufficiency.

Symptoms

Loss of appetite
Weakness
Ataxia
Depression
Jaundice
Abdominal swelling
Diarrhea
Dysphagia
Colic
Muscle tremors
Abortion
Rapid weight loss
Reduced fecal output
Pyrexia
Circling
Head-pressing
Convulsions
Coma

Diagnosis

  • History
  • Clinical signs
  • Physical exam
  • Blood test - opaque serum or plasma with TG concentrations greater than 5.6 mmol/l

Treatment

TherapiesDetails
Nutritional support
Fluid therapy
Drug therapy
Parenteral glucose administration (with or without insulin)
Treatment of concurrent disease

Scientific Research

General Overviews

Risk Factors

  • Insulin resistance (IR)
  • Pregnancy