Clostridial myonecrosis

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Clostridial Myonecrosis

Malignant Edema

Clostridial myonecrosis is a rare and acute, bacterial disease associated with Clostridium spp., spore-forming, rod-shaped, Gram-positive, anaerobes which are known to produce a variety of toxins, many of which are fatal. Clostridium spp. are commonly found throughout the environment and inhabit soil, sewage, and marine sediments, as well as the intestines of both animals and humans.

Clostridial myonecrosis can occur from giving horses intramuscular injections or from unclean wounds, particularly those caused by sharp objects. Complications of infection can cause haemolytic anaemia, hepatopathy, osteitis, and transient hypertrophic cardiomyopathy.

Symptoms

High fever
Oozing from wound
Stiffness
Swelling
Behavior changes
Circling
Collapse

Diagnosis

  • Clinical signs
  • Biopsy

Treatment


TreatmentDetails
A combination of surgical fenestration/debridement and high dose intravenous antibiotic therapy
Intravenous fluid therapy
Blood transfusion

Prognosis

With rapid diagnosis and therapeutic intervention horses may have up to a 81% chance of survival.

Scientific Research References

Good Overviews