- Dantrolene is a skeletal muscle relaxant which is taken orally for the prevention or treatment of malignant hyperthermia-associated myopathy exertional rhabdomyolysis in horses. It can also be used in poisonings which can result in severe hyperthermia or malignant hyperthermia; Monamine oxidase inhibitors, halogenated hydrocarbons, atropine, dinitrophenol, metaldehyde, cocaine, amphetamines, Ergot alkaloids (Claviceps), Tall Fescue (Festuca), Jimsonweed (Datura), Ryegrass (Lolium), and spent Hops (Lumulus). 10-25 mg/kg IV slowly PRN.
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